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Hindi Journal of Pharmaceutical Sciences & Emerging DrugsISSN: 2380-9477
Virendra S. Rana Author
Subjects of specialization
Affiliation
Pharmacology, Pharmaceutical Sciences, Medicinal Chemistry, Drag reduction, Drug Therapy
Indian Agricultural Research Institute (Indian Council of Agricultural Research), Pusa, New Delhi, India.
Biography
Virendra S. Rana; Indian Agricultural Research Institute (Indian Council of Agricultural Research), Pusa, New Delhi, India. He stated, "Swertiamarin, a bitter and potent hepatoprotective iridoid glucoside (~20 mg) was isolated by Centrifugal Partition Chromatography coupled with Diode Array Detector (DAD) from the crude methanolic extract (1.0 g) of its aerial parts using a biphasic solvent system composed of chloroformmethanol- water (86:74:20, v/v) in ascending mode for the first time. The purity of the compound was found to be >97%. The structure of swertiamarin was determined using spectroscopic."
Publications
Research Article Subscription
Separation and Identification of Swertiamarin from Enicostema axillare Lam.Raynal by Centrifugal Partition Chromatography and Nuclear Magnetic Resonance-Mass Spectrometry*
Author(s): Virendra S. Rana,
Separation and Identification of Swertiamarin from Enicostema axillare Lam.Raynal by Centrifugal Partition Chromatography and Nuclear Magnetic Resonance-Mass Spectrometry*
Enicostema axillare, a bitter herb, has been used for the treatment of diabetes in traditional system of medicine in India. Swertiamarin, a bitter and potent hepatoprotective iridoid glucoside (~20 mg) was isolated by Centrifugal Partition Chromatography coupled with Diode Array Detector (DAD) from the crude methanolic extract (1.0 g) of its aerial parts using a biphasic solvent syst... view more»
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