Zhang FF Author

Research Article Open Access

Effects of Differently Processed Rehmannia Roots on Dexamethasone-induced Side Effects in Rats

Author(s):

Zhang FF, Wen XS*, Lu YF, Luo SF, Lv C and Xian CJ

Background: There are three differently processed rehmannia roots, namely fresh, dried and steamed rehmannia roots (FRR, DRR and SRR), which have different indications according to the theory of traditional Chinese medicine (TCM).
Objective: To confirm the effects of different rehmannia roots on dexamethasone (Dex) treatment induced side effects, which belong to Yin Deficiency Syndrome in TCM.
Materials and Methods: Rats were subcutaneously injected with Dex (0.1m g/kg) and orally administrated with different roots (2.16 g/kg) for 28 days, with metformin (Met, 0.25 g/kg) as a reference substance. Food intake, blood cell count, and organ weight were recorded, and hepatic glycogen and serum insulin, ... view more»

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