Journal of Forensic Toxicology & PharmacologyISSN: 2325-9841

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Research Article, J Forensic Toxicol Pharmacol Vol: 5 Issue: 2

Application of NeedlEx® to the Analysis of N-methyl O-aryl Carbamates in Urine and Serum Samples

Suzuki Y1,2*, Kawabata M1, Ishiwata T1, Fujimura K3, Ishizawa F2 and Honda K2
1Forensic Science Laboratory, Ibaraki Prefectural Police Headquarters, 978-6 Kasahara-cho Mito, Ibaraki 310, Japan
2Department of Legal Medicine, University of Tsukuba, 1-1-1 Tennoudai Tukuba, Ibaraki 305, Japan
3Shinwa Chemical Industries, Ltd., 50-2 Kagekatu-cho Fushimi-ku Kyoto, Kyoto 612, Japan
Corresponding author : Suzuki Y
Department of Legal Medicine, University of Tsukuba, 1-1-1 Tennoudai Tukuba, Ibaraki 305, Japan
Tel: +81-29-301-0110
E-mail:
[email protected]
Received: December 15, 2016 Accepted: December 27, 2016 Published: December 31, 2016
Citation: Suzuki Y, Kawabata M, Ishiwata T, Fujimura K, Ishizawa F, et al. (2016) Application of NeedlEx® to the Analysis of N-methyl O-aryl Carbamates in Urine and Serum Samples. J Forensic Toxicol Pharmacol 5:2. doi: 10.4172/2325-9841.1000149

Abstract

The use of carbamates has been implicated in several suicides and in accidental poisoning. Rapid identification of these carbamates in clinical samples can direct the course of medical intervention and help save lives. In this study, we describe a new, operationally simple, and rapid method that employs a gas chromatograph (GC) or gas chromatograph-mass spectrometer (GC-MS) coupled to a NeedlEx® to analyze such toxic carbamates. NeedlEx®, a needle packed with media for the selective adsorption of volatile organic compunds, is idealy suited for use in such methods.

Keywords: Carbamates; Poisoning; Gas chromatography; Mass spectroscopy;NeedlEx®

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