Journal of Addictive Behaviors,Therapy & RehabilitationISSN: 2324-9005

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Case Report, J Addict Behav Ther Rehabil Vol: 3 Issue: 2

Use of Dexmedetomidine for the Management of Excited Delirium in a Polysubstance Dependence Trauma Patient

Jonas P. DeMuro*, Michael Mongelli and Adel F. Hanna
Winthrop University Hospital, Department of Surgery, Division of Trauma& Critical Care, 259 First Street, Mineola NY 11501, USA
Corresponding author : Jonas P. DeMuro, MD, FACS
Winthrop University Hospital, Department of Surgery, Division of Trauma & Critical Care, 259 First Street, Mineola NY 11501, USA
Tel: 516.663.3300; Fax: 516.663.8707
E-mail: [email protected]
Received: March 05, 2014 Accepted: April 22, 2014 Published: April 24, 2014
Citation: DeMuro JP, Mongelli M, Hanna AF (2014) Use of Dexmedetomidine for the Management of Excited Delirium in a Polysubstance Dependence Trauma Patient. J Addict Behav Ther Rehabil 3:2. doi:10.4172/2324-9005.1000122

Abstract

Use of Dexmedetomidine for the Management of Excited Delirium in a Polysubstance Dependence Trauma Patient

Management of acute delirium in patients with polysubstance dependence remains a challenge due to the overlap in symptoms between the delirium and the withdrawal syndromes from multiple agents. We describe a recent case of a trauma patient after a motor vehicle accident with polysubstance dependence including opioids, benzodiazepines and cocaine. The patient developed acute agitated delirium, requiring mechanical ventilation for respiratory insufficency. His delirium was treated with haloperidol and lorazepam, but to facilitate rapid control and possible prevention of a withdrawal syndrome we used dexmedetomidine in the acute phase. The early use of dexmedetomidine may facilitate a safe and effective treatment modality in agitated delirium as well as a possible preventive measure in controlling any severe withdrawal syndrome.

Keywords: Dexmedetomidine, Substance abuse withdrawal, Polysubstance abuse, Rapid detoxicification

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