Journal of Liver: Disease & TransplantationISSN: 2325-9612

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The Effectiveness of Venesection Therapy for Haemochromatosis Symptoms

The Effectiveness of Venesection Therapy for Haemochromatosis Symptoms

Hereditary haemochromatosis (HH) is an autosomal recessive disorder, characterized by iron overload, and it is the commonest genetic condition affecting people of northern European ancestry. In most HH cases (>90%), a homozygous C282Y missense mutation on the HFE gene is the causeThe aim of this study was to determine if (1) the main symptoms of haemochromatosis, fatigue and arthritis, are improved by venesection therapy, and (2) to determine the number of venesections required to reach the target ferritin level.

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