Journal of Nanomaterials & Molecular NanotechnologyISSN: 2324-8777

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Conference Proceeding, J Nanomater Mol Nanotechnol S Vol: 0 Issue: 2

Analysis of Cell-Derived Microparticles with Highly Precise Nanotechnological Methods

Solène Cherré1*, Ole Østergaard2, Niels H. H. Heegaard2,Noemi Rozlosnik1
1Technical University of Denmark, Department of Micro- and Nanotechnology,Oersteds Plads 345 East, DK-2800 Kongens Lyngby, Denmark
2Statens Serum Institut 5 Artillerivej, DK-2300 Copenhagen S, Denmark
Corresponding author : Solène Cherré
Technical University of Denmark, Department of Micro- and Nanotechnology, Oersteds Plads 345 East, DK-2800 Kongens Lyngby, Denmark
Tel: +45 914 184 34
E-mail: [email protected]
Received: April 23, 2014 Accepted: July 22, 2014 Published: July 25, 2014
Citation: Cherré S, Østergaard O, Heegaard NHH, Rozlosnik N (2014) Analysis of Cell-Derived Microparticles with Highly Precise Nanotechnological Methods. J Nanomater Mol Nanotechnol S2:004. doi:10.4172/2324-8777.S2-004

Abstract

Analysis of Cell-Derived Microparticles with Highly Precise Nanotechnological Methods

Cell-derived microparticles have gained a broad interest in the past years. Being released by blood cells upon activation or induction of apoptosis, they have a great potential as novel diagnostic markers and their investigation can bring new knowledge into the pathogenesis of various diseases. However, new analysis methods are required to correctly and reliably investigate these small biological particles (between 50 and 1000 nm). In this work, we aimed at developing an in vitro population of cell-derived microparticles from endothelial cells. The size of the microparticles was analysed by atomic force microscopy.

Keywords: Cell-derived microparticles; Atomic force microscopy; Apoptosis

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