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Hindi Journal of Neuroscience & Clinical Research
Jun Wu Author
Subjects of specialization
Affiliation
Anti-dipeptidylpeptidase like protein 6 antibody, Nystagmus, Ataxia, Autoimmune encephalitis
Prodromal Infection Trigger Acute Onset Anti-DPPX Encephalitis without CNS Hyperexcitability Symptoms: A Case Report Department of Neurology, Peking University Shenzhen Hospital, Shenzhen, China
Biography
Jun Wu belong to the Department of Neurology, Peking University Shenzhen Hospital, intrested the field of Autoimmune encephalitis; Anti-dipeptidylpeptidase like protein 6 antibody; Nystagmus; Ataxia from Shenzhen, China
Publications
Case Report Open Access
Prodromal Infection Trigger Acute Onset Anti-DPPX Encephalitis without CNS Hyperexcitability Symptoms: A Case Report
Author(s): Xuhui Chen, Juanjuan Chen, Jun Wu, Ang Li and Jun Hu
Dipeptidylpeptidase-like protein-6 (DPPX) antibody associated encephalitis can present with protracted encephalitis, symptoms of central nervous system(CNS) hyperexcitability, and cerebellar signs. Most of these patients onset subacutely and have diarrhea in the initial phase. We report a 26-year-old Chinese female, who had ten days history of upper respiratory tract infection, followed by headache, dizziness, gait instability suddenly. Neurological examination demonstrated prominent vertical nystagmus, astasia and cognitive impairment. CSF testing for neuronal autoantibodies revealed DPPX antibody IgG titer of 1:1. After treatment with IV methylprednisolone combined with IV immunoglobulin, her neurological symptoms improved markedly. This case illustrated that anti-DPPX autoimmune ence... view more»
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