PHD Author

Research Article Open Access

The Protective Effect of a Novel Coumarinic Derivative on Streptozotocin Induced Diabetic Rats

Author(s):

Nahla S. Zidan, Al-Shehri Fawziah S, Mohamed Sakran and Mohamed Elbakry, PHD

The Protective Effect of a Novel Coumarinic Derivative on Streptozotocin Induced Diabetic Rats

Diabetes mellitus (DM) affects more than 415 million persons worldwide. It is one of the most important causative factors of mortality in the developing countries. It was established that Streptozotocin (STZ) is a chemical compound that induces diabetic complications in rats. This study aimed to examine the ability of novel coumarine-caffeic acid derivative: Ethyl-3-(3, 4- dihydroxyphenyl) acrylamido--5-methoxy-1-(4- methoxyphenyl)-10-methyl-8-oxo-1, 8-dihydropyrano [3, 2-f] chromene-2-carboxylate (Compound I) to reduce the diabetic complications induced by STZ.Diabetes... view more»

DOI: 10.4172/2324-9323.1000195

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