Biography
Dr Alessandro Poggi has been working on cellular and tumor immunology for more than 30 years. He is authors of 203 original articles published on indexed journals and he is a reviewer of several scientific journals. Starting from his first doctoral degree in Biological Sciences (1982), he worked on functional characteristics of leukocyte subsets. After his Post-Doctoral Fellow training at the Ludwig Cancer Institute in Lausanne, Switzerland (1985-1987), he has been appointed as Assistant Member at the IST (Immunopathology Unit) in Genoa studying natural killer cell development and function, molecular aspects of survival of subsets of leukocytes and the role of mesenchymal stromal and stem cells in tumor microenvironment. In 2000, he has taken his second doctoral degree in Medicine and Surgery. He has got specialization in General Pathology (1986) and Allergy and Clinical Immunology (2004). He has the scientific abilitation as full professor in general and Clinical Pathology as well as in Molecular Biology (2014). From July 2009, he is director of the Molecular Oncology and Angiogenesis Unit at the Ospedale Policlinico San Martino in Genoa. At present, his main research interest is the tumor microenvironment (TME) and regulation of antitumor immune response. This focusing on the molecular mechanisms that can be involved in the relieve of immunosuppression mediated by mesenchymal stromal cells (MSC). Very recently, he is setting up a section of digital pathology to study in colon rectal carcinoma MSC in TME and identify markers relevant to trigger the TME to become immunostimulant instead of immunosuppressive. Further, to this aim, he is studying the delivery with nanovectors of immune activating drugs to tumor in three dimensional culture systems.
Research Interest
Mechanisms of tumor escape from immune system-mediated control, cell activation and signal transduction, activating and inhibiting receptor molecules, molecular mechanisms of immune-regulation, mesenchymal stromal cells and interaction with immune system.
Related Publications
-
Post-zygotic Mosaic Mutation in Normal Tissue from Breast Cancer Patient
Research Article: J Mol Biol Methods 2020, 3:1
DOI:
Ryong Nam Kim
-
Past Conference Report on Annual Conference on Mechatronics, Systems Engineering and Automation
Past Conference Report: J Mol Biol Methods
DOI:
PA Kyriacou
-
Market analysis of System Biology
Market Analysis: J Mol Biol Methods
DOI:
Gottfried Baier
-
Market Analysis for the 6th International Conference on Molecular Biology and Nucleic Acids 2020
Market Analysis: J Mol Biol Methods
DOI:
Lata Balakrishnan
-
Outstanding Scientific Contributions and Achievement Awards
Awards 2020: J Mol Biol Methods
DOI:
Jean-Yves Masson
-
The Laws of Genetics Apply Even If You Refuse to Learn Them
Market Analysis: J Mol Biol Methods
DOI:
Elsayed Ahmed Elnashar
-
Market Analysis for the Respirology, Lung & Chest 2020
Awards 2020: J Mol Biol Methods
DOI:
ROSKAMS JANE
-
System Biology and Genetics Conference 2020 Announcement Nov 23-24 | Miami, USA
2020 Conference Announcement: J Mol Biol Methods
DOI:
Ludger Hengst
-
Awards 2020 on Glycobiology
Awards 2020: J Mol Biol Methods
DOI:
Dr. Alireza Heidari
-
Potential False Negatives in the Molecular Diagnostics of COVID-19 Infection: Experience of an Italian Laboratory during the COVID-19 Epidemic
Short Communication: J Mol Biol Methods 2020, 3:1
DOI:
Alessandro Pancrazzi*, Roberta Perticucci, Stefania Vecchietti, Gianluca Magrini, Guendalina Vaggelli, Pasqualino Magliocca, Angelo Galano, Manuela Mafucci, Irene Alessandra Galanti and Agostino Ognibene
-
Vaccines & Vaccination Theme: Advances in Immunology & Vaccine Technology and their Impact
Past Conference Report: J Mol Biol Methods
DOI:
Ahmed Hegazi
-
6th International Conference on Public Health and Nutrition
Awards 2020: J Mol Biol Methods
DOI:
Galyna Khrushch
-
Award Advanced Genetics
Awards 2020: J Mol Biol Methods
DOI:
Elsayed Ahmed Elnashar
-
Young Research Forum on Molecular Biology & Biochemistry
Young Research Forum: J Mol Biol Methods
DOI:
PA Kyriacou
-
Young Scientist Awards for Nucleic Acid 2020
Young Research Forum: J Mol Biol Methods
DOI:
Lata Balakrishnan
-
Young Researchers Forum - Young Scientist Awards Microbiology Conference 2020
Young Research Forum: J Mol Biol Methods 2020, 3:1
DOI:
Dr. Yavuz Selim Silay
-
Attention Deficit and Hyperactivity Disorder May be Linked to Renalase Enzyme Amount Synthesized in Brain?
Editorial: J Mol Biol Methods 2020, 3:1
DOI:
Suleyman Aydin
-
An Alternative Approach to Solving the Opioid Epidemic: Expanding the Use of Non-Pharmacologic Techniques for Acute and Chronic Pain Management
Commentary: J Mol Biol Methods 2018, 1:1
DOI:
Paul F White
-
Molecular Basis and Engineering of Enzymes Stereospecificity
Review Article: J Mol Biol Methods 2018, 1:1
DOI:
Aliyu Adamu, Firdausi Aliyu, Fahrul Huyop and Roswanira Abdul Wahab
-
Chloroplast DNA: A Promising Source of Information for Plant Phylogeny and Traceability
Review Article: J Mol Biol Methods 2018, 1:1
DOI:
Freitas AS, da Anunciação RR, D’Oliveira-Matielo CB and Stefenon VM
-
CYPs Genotyping, Essential Hypertension and Frequencies of Mutant Alleles in an Uzbek Population
Research Article: J Mol Biol Methods 2018, 1:1
DOI:
Nagay AV, Khamidullayeva GA, Srojidinova NZ and Kurbanov RD
-
New Era of Metabolism from Glucose to Ketone Body with Beneficial Effects
Opinion Article: J Mol Biol Methods 2018, 1:1
DOI:
Hiroshi Bando