Journal of Genital System & DisordersISSN: 2325-9728

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Editorial, J Genit Syst Disor Vol: 0 Issue: 0

Genital Warts: Stepwise Approach to Cure

Marlene Shehata*, Fady Youssef and Alan Pater
Pharmaceuticals, Southwestern Ontario, Canada
Corresponding author : Marlene Shehata
Clinical Pharmacist Consultant/Cardiovascular Geneticist, Canada
E-mail: [email protected]
Received: June 19, 2012 Accepted: June 20, 2012 Published: June 22, 2012  doi:10.4172/2325-9728.1000e101
Citation: Shehata M, Youssef F and Pater A (2012) Genital Warts: Stepwise Approach to Cure. J Genit Syst Disor 1:1 doi:10.4172/jgsd.1000e101

Abstract

Genital Warts: Stepwise Approach to Cure

Genital warts or venereal warts are the most common sexually-transmitted disease caused by the non-oncogenic human papilomavirus (HPV). Genital warts are highly contagious and sexual contact should be avoided when genital warts are present. Canadians, especially younger Canadians, perceive genital warts with a fair degree of social stigma and genital warts have a negative impact on their psyche. It is essential to note that there is no single effective cure for genital warts and that recurrence is always a possibility. As such, genital warts are associated with a significant burden of illness and costs to the healthcare system.

Keywords:

Genital warts or venereal warts are the most common sexually-transmitted disease caused by the non-oncogenic human papilomavirus (HPV) [1]. Genital warts are highly contagious and sexual contact should be avoided when genital warts are present. Canadians, especially younger Canadians, perceive genital warts with a fair degree of social stigma and genital warts have a negative impact on their psyche [2]. It is essential to note that there is no single effective cure for genital warts and that recurrence is always a possibility [3,4]. As such, genital warts are associated with a significant burden of illness and costs to the healthcare system [5].
Current therapeutic options include surgical and non-surgical strategies [3]. Surgical strategies include ablation/excisional therapies. Ablative/excisional therapies include cryotherapy, laser treatment, electrosurgery and scissor excision. In Canada, cryotherapy, freezing the wart using liquid nitrogen is the most common procedure and is commonly done in physicians’ offices. Response rates are high with few side effects.
Non-surgical treatments include cytotoxic agents and immunomodulators. Cytotoxic agents such as podophyllum resin, podophyllotoxin, and trichloroacetic acid are common agents. Podophyllum resin and trichloroacetic acid are topically applied by a health care practitioner, whereas podofilox can be topically applied at home. Immunomodulators such as Imiquimod (Aldara®), interferon alpha-n3 (Roferon A®), and 5-fluorouracil (Efudex®) are available in Canada. Local side effects such as erythema, oedema, itching and pain can occur with all treatments [4]. With the numerous challenges surrounding the treatment of genital warts along with the negative impact they have on the psychology of infected individuals, the primary prevention of HPV infection through vaccination is a key component in decreasing the incidence of the disease.

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