Journal of Nanomaterials & Molecular NanotechnologyISSN: 2324-8777

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Research Article, J Nanomater Mol Nanotechnol Vol: 6 Issue: 4

Platinum and Copper Supported in Functionalized Titania Nanoparticles for the Treatment of Cervical and Prostate Cancer

Lopez T1,2*, Larraza P1 and Gomez E3

1Universidad Autónoma Metropolitana-Unidad Xochimilco, Calzada del Hueso 1100, Villa Quietud, Coyoacán, Zp 04960, Mexico

2Federico Gómez Children’s Hospital of Mexico, Dr. Márquez St. 162, Doctores, Cuauhtémoc, Zp 06720, Mexico

3Humboldt-Universität zu Berlin, Institut für Physik, Germany

*Corresponding Author : Tessy Lopez Goerne
Universidad Autónoma Metropolitana-Unidad Xochimilco, Calzada del Hueso 1100, Villa Quietud, Coyoacán, Zp 04960, Mexico
Tel: (551) 951-5658
E-mail:
[email protected]

Received: June 05, 2017 Accepted: August 01, 2017 Published: August 06, 2017

Citation: Lopez T, Larraza P, Gomez E (2017) Platinum and Copper Supported in Functionalized Titania Nanoparticles for the Treatment of Cervical and Prostate Cancer. J Nanomater Mol Nanotechnol 6:4. doi: 10.4172/2324-8777.1000227

Abstract

Today, cancer is one of the main causes of mortality. The most common treatments are chemotherapy, surgery, radiology and radiosurgery. The catalytic nanomedicine is a new research branch focused on the preparation of nanobiomaterials with medical applications to create a targeted therapy. The goal of this study was to determine the cytotoxic effect of the platinum nanoparticle (NPt) and the copper nanoparticle (NP-Cu) in lines of cancer cells as well as healthy cells for the cervical uterus cancer (HeLa), prostate cancer (DU 145). The catalyst nanoparticles used to break the bonds C-C, C-N and C=O in nitrogenous bases were synthesized in a sol-gel process. It is proven that they were biocompatible and non-toxic. Cell barriers were crossed with platinum and copper supported on functionalized titania (TiO2). In vitro tests were performed giving as a result that the NPt nanoparticles are much slower than the NP-Cu ones.

Keywords: Nanoparticles; Platinum; Copper; HeLa; DU 145

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