Journal of Nanomaterials & Molecular NanotechnologyISSN: 2324-8777

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Research Article, J Nanomater Mol Nanotechnol S Vol: 0 Issue: 4

Water-Soluble Multimodal Core/ Shell NaGdF4:Yb,[email protected] Upconverting Nanoparticles for Cancer Diagnostics

Karpus L1, Baziulyte D2, Mikalauskaite I3, Stalnionis M1, Jarockyte G1, Poderys V1, Sakirzanovas S2, Beganskiene A3, Streckyte G4, Karabanovas V1,5* and Rotomskis R1,4
1Biomedical Physics Laboratory, National Cancer Institute, Lithuania
2Department of Applied Chemistry, Faculty of Chemistry, Vilnius University, Lithuania
3Department of Inorganic Chemistry, Faculty of Chemistry, Vilnius University, Lithuania
4Biophotonics Laboratory, Laser Research Centre, Vilnius University, Lithuania
5Department of Chemistry and Bioengineering, Vilnius Gediminas Technical University, Lithuania
Corresponding author : Karabanovas
Department of Chemistry and Bioengineering, Vilnius Gediminas Technical University, Lithuania
E-mail: [email protected]
Received: May 10, 2016 Accepted: October 12, 2016 Published: October 17, 2016
Citation: Karpus L, Baziulyte D, Mikalauskaite I, Stalnionis M, Jarockyte G, et al. (2016) Water-Soluble Multimodal Core/Shell NaGdF4:Yb,[email protected]4 Upconverting Nanoparticles for Cancer Diagnostics. J Nanomater Mol Nanotechnol S4:004. doi: 10.4172/2324-8777.S4-004

Abstract

Water-Soluble Multimodal Core/ Shell NaGdF4:Yb,[email protected] Upconverting Nanoparticles for Cancer Diagnostics

Upconverting nanoparticles (UCNPs) are promising new generation of imaging probes capable of working as theranostic agents. Upconversion is a nonlinear optical process that converts two or more photons to a higher-energy out-put photon. UCNPs are guesthost systems where trivalent lanthanide ions are dispersed as a guest in an appropriate dielectric host lattice with a dimension less than 30nm. Generally, upconversion emission arises from 4f-4f orbital electronic transitions.

Keywords: Upconverting nanoparticles; Multimodal imaging; Cancer theranostics

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