Journal of Genetic Disorders & Genetic Reports ISSN: 2327-5790

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Research Article, J Genet Disor Genet Rep Vol: 3 Issue: 1

Are Antimullerian Hormone and its Receptor Genes Associated with Low Ovarian Response?

Chelsi Goodman1, Hosam Zaki2, Larry Fischel3, Hisham Greiss3 and Carolyn Coulam3,4*
1Chicago Medical School, Rosalind Franklin University of Medicine and Science,North Chicago, IL, USA
2Ganin Fertility Center, Cairo, Egypt
3Fertility and Cryogenics Laboratory, Downers Grove, IL, USA
4Reproductive Medicine Institute, Evanston, IL, USA
Corresponding author : Dr. Carolyn Coulam
Reproductive Medicine Institute, 2500 Ridge Ave, Suite 200, Evanston, IL 60201, USA
Tel: 847 869 7777; Fax: 847 869 7782;
E-mail: [email protected]
Received: February 03, 2014 Accepted: March 06, 2014 Published: March 12, 2014
Citation: Goodmana C, Zakib H, Fischelc L, Greissc H, Coulam C (2014) Are Antimullerian Hormone and its Receptor Genes Associated with Low Ovarian Response?. J Genet Disor Genet Rep 3:1. doi:10.4172/2327-5790.1000112

Abstract

Are Antimullerian Hormone and its Receptor Genes Associated with Low Ovarian Response?

One of the most frustrating problems in the treatment of infertility is that of poor ovarian response to stimulation. It therefore, would be advantageous to have a genetic marker that could predict low ovarian reserve at a young age before the impact of low ovarian reserve affects a woman’s fertility. Antimullerian hormone (AMH) has emerged as the the most accurate measure of ovarian reserve. The purpose of the present study is to investigate the correlation between AMH and AMH Receptor II (AMHRII) polymorphisms and low ovarian reserve.

Keywords: AMH gene polymorphisms; AMH receptor gene II polymorphisms; Low ovarian reserve

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