Journal of Food and Nutritional DisordersISSN: 2324-9323

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Research Article, J Food Nutr Disor Vol: 3 Issue: 5

Associations of Circulating Leptin Concentrations with Metabolic and Inflammatory Risk Markers in Extremely Obese Subjects

Sophie Holst Eckbo1, Eli Heggen1, Lars Retterstol2 and Serena Tonstad1*
1Preventive Cardiology Clinic, Oslo University Hospital, Oslo, Norway
2Department of Medical Genetics, Oslo University Hospital, Oslo, Norway
Corresponding author : Serena Tonstad, MD PhD
Preventive Cardiology, Oslo University Hospital; N-0047 Oslo, Norway
Tel: +47 22 11 79 39; Fax: +47 22 11 99 75;
E-mail: [email protected]
Received: March 11, 2014 Accepted: August 28, 2014 Published: September 02, 2014
Citation: Eckbo SH, Heggen E, Retterstol L, Tonstad S (2014) Associations of Circulating Leptin Concentrations with Metabolic and Inflammatory Risk Markers in Extremely Obese Subjects. J Food Nutr Disor 3:5. doi:10.4172/2324-9323.1000153

Abstract

Associations of Circulating Leptin Concentrations with Metabolic and Inflammatory Risk Markers in Extremely Obese Subjects

Background: Reliable and robust markers of obesity and cardiovascular morbidity are needed for accurate risk estimation, intervention and follow-up. This is even more paramount in extremely obese patients, who are most likely to suffer from health hazards. Metabolic risks may not increase in direct proportion to degree of obesity. The study aim was to examine associations between leptin concentrations and metabolic and inflammatory cardiovascular risk markers in the extremely obese.

Keywords: Cardiovascular disease; Leptin; Obesity; Risk markers; Inflammation

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