Journal of Clinical Nutrition and Metabolism

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Ioanna-Panagiota Kalafati Author

dedousi@hua.gr

Subjects of specialization
Nutrition Nutritional, Statistical Genetics, Human Nutrition, Metabolic Diseases

Affiliation
Department of Dietetics and Nutritional Science, Harokopio University, Athens, Greece

Biography

Ioanna Kalafati is at Harokopio University in Athens, Greece. Her top areas of expertise are Nonalcoholic Steatohepatitis, Non-Alcoholic Fatty Liver Disease, Obesity, and Asthma. Her clinical research consists of co-authoring 13 peer reviewed articles in the past 15 years.

Publications

Review Article Open Access

Nutrigenetics of Non-Alcoholic Fatty Liver Disease: What do we know so Far?

Author(s):

George V Dedoussis, Chara Vezou and Ioanna-Panagiota Kalafati

Non-alcoholic fatty liver disease (NAFLD) tends to be a new epidemic. It is now considered as the new element of metabolic syndrome, since it is highly correlated with obesity and diabetes mellitus type II. However, there are some patients whose disease is not linked to metabolic abnormalities; the etiology of this type of disease is the genetic background. Main genetic contributors to NAFLD are PNPLA3, TM6SF2 and GCKR. Genetic variations in these loci have been associated with NAFLD onset and progression. Moreover, dietary habits and nutrients’ intake can affect the disease status. Diet composition, such as anti-inflammatory and pro-inflammatory polyunsaturated fatty acids (PUFAs) a... view more»

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