Journal of Genetic Disorders & Genetic Reports ISSN: 2327-5790

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Case Report, J Genet Disor Genet Rep Vol: 2 Issue: 2

Congenital Cerebral Ischemic Lesions in Monochorionic Twins

Olajide Dolapo* and Ravi Kudumula
University of Tennessee Health Science Center, Memphis, TN, USA
Corresponding author : Dr. Olajide Dolapo
University of Tennessee Health Science Center, Memphis, TN, USA
E-mail: [email protected]
Received: August 30, 2013 Accepted: November 11, 2013 Published: November 18, 2013
Citation: Dolapo O, Kudumula R (2013) Congenital Cerebral Ischemic Lesions in Monochorionic Twins. J Genet Disor Genet Rep 2:2. doi:10.4172/2327-5790.1000107

Abstract

Congenital Cerebral Ischemic Lesions in Monochorionic Twins

Congenital cerebral anomalies arising from in-utero ischemic events are rare. Schizencephaly and hydranencephaly occurring together in both surviving monochorionic twins is even rarer. We report a case of monochorionic female twins of 31 weeks gestation. The twins were diagnosed at 25 weeks, one with hydranencephaly and the other with schizencephaly. These defects are commonly presumed to be the result of in utero disruption of previously normally formed structures through a secondary vascular exchange from a dead to a living monozygotic twin through placental vascular anastomoses.

Keywords: Monochorionic; Hydranencephaly; Schizencephaly

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