Journal of Food and Nutritional DisordersISSN: 2324-9323

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Research Article, J Food Nutr Disord Vol: 6 Issue: 5

Effect of Afghan Chehelghoza (Pinus gerardiana L.) on Sperm Parameters of Male Rats

Shirin Safari1, Mohammad Yousefi2, Amena Khawari1, Meysam Sajjadi1, Mohammad Latif Nazari1, Adamkhan Alipour3, Mohammad Hossein Salehi4 and Yousof Mousavi1*

1Researches and Technology Center, Khatam Al-Nabieen University, Kabul, Afghanistan

2Department of Biotechnology and Seed Production, Agriculture Faculty, Kabul University, Kabul, Afghanistan

3Department of Biochemistry, Cheragh Medical University, Kabul, Afghanistan

4Department of Biology, Kabul Medical University, Kabul, Afghanistan

*Corresponding Author : Yousof Mousavi
Department of Physiology, Khatam Al- Nabieen university, Karte 4, 1st street, Kabul, Afghanistan

Received: October 12, 2017 Accepted: October 27, 2017 Published: October 31, 2017

Citation: Safari S, Yousefi M, Khawari A, Sajjadi M, Nazari ML, et al. (2017) Effect of Afghan Chehelghoza (Pinus gerardiana L.) on Sperm Parameters of Male Rats. J Food Nutr Disord 6:5. doi: 10.4172/2324-9323.1000237


Infertility has become one of the controversial issues recently that are affected by environmental factors. Of the effective factors in this regard is the plants and its derivatives that each of them has variable effects. The plants with the special chemical substance such as phytosterols could be significantly effective. Chehelghoza is one of the Afghan native plants that contain a special phytosterol named beta sitosterol (BS) that have been proved to decrease the fertility. Adult male Sprague-Dawley rats from an inbreed colony were selected. Thirty-two male rats were randomly divided into four groups. Rats in groups 1, 2, 3 received 5, 25, and 50 percent Chehelghoza in their daily food, respectively for 14 days. Rats in group 4 (as the control) received their daily food without Chehelghoza for 14 days. The result of our study showed that different doses of Chehelghoza significantly decrease the sperm motility, sperm count, and TG (Triglyceride) plasma levels. We consider that Chehelghoza containing phytosterol can reduce male fertility factors.

Keywords: Afghan chehelghoza; Beta-sitosterol; Infertility; Phytosterol; Sperm parameter

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