La Prensa MedicaISSN: 0032-745X

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Research Article, Prensa Med Argent Vol: 102 Issue: 2

Features of Cytokine Profile in Patients with Progressive TB-Induced Pulmonary Fibrosis Characterized by Various Intensities of Pulmonary Destructive Changes

Abstract

Features of Cytokine Profile in Patients with Progressive TB-Induced Pulmonary Fibrosis Characterized by Various Intensities of Pulmonary Destructive Changes

Production of pro- and anti-inflammatory cytokines (IFN-γ, IL-2, TNF-α, IL-8, IL-4, IL-10) in patients with pulmonary TB infection with various spread and severity of the process were investigated in in vitro PPD- and PHA-stimulated peripheral blood mononuclear cells (PBMCs). It was demonstrated that each type of MDR-TB lung fibrosis is determined by specific traits of a multilevel cytokine network functioning according to activity of cytokine-producing cells.

Keywords: Tuberculosis; Multidrug-resistant tuberculosis; Phytohemagglutinin; Interleukin

international publisher, scitechnol, subscription journals, subscription, international, publisher, science

Track Your Manuscript

H5 Index

SCImago Journal & Country Rank
Awards Nomination