Case Report, Jgsd Vol: 8 Issue: 1
Genital Well-Demarcated Plaques: What’s your Diagnosis?
Bennani M*, Dahouki S, Benkirane S, Elloudi S, Baybay H and Zahra F
Mernissi Department of Dermatology, University Hospital Hassan II of Fez, Fes 30050, Morocco
Received:August 13, 2019 Accepted:August 26, 2019 Published: September 04, 2019
Citation: Bennani M, Dahouki S, Benkirane S, Elloudi S, Baybay H, et al. (2019) Genital Well-Demarcated Plaques: What’s your Diagnosis? J Genit Syst Disord 8:1.
Multiple small erythematous plaques of different size, welldefined
with regular contours and smooth surface in place and
scaly by others, at the level of the body of the penis of a
young man of 28 years, and the balano-preputial groove. A
cutaneous biopsy was performed demonstrating a
moderately acanthotic epidermis with moderate
papillomatosis surmounted by a thickened
orthokeratotic corneal layer with a continuous compact
continuous parakeratosis with focally rare polynuclear
Keywords: Penis; Chronic inflammatory; Genital psoriasis; Lymphocytes
Penis; Chronic inflammatory; Genital psoriasis; Lymphocytes
28-year-old man, no notion of atopic personal or family or history of lesion evolving by thrust remission in the body or the scalp, no unprotected sex, who has had 15 days of genital lesions pruriginous at the beginning then becoming asymptomatic.
The rest of the clinical examination didn ’ t show any other anomalies.
The patient and his wife were very worried.
A cutaneous biopsy was performed demonstrating a moderately acanthotic epidermis with moderate papillomatosis surmounted by a thickened orthokeratotic corneal layer with a continuous compact continuous parakeratosis with focally rare polynuclear neutrophils.
The edematous papillary dermis contains a few elongated vessels, accompanied by slight perivascular inflammatory cuffs essentially made of lymphocytes and some histiocytes. PAS staining does not show mycelium.
Dermatological examination: Multiple small erythematous plaques of different size well-defined with regular contours and smooth surface in place and scaly by others, at the level of the body of the penis, and the balano-preputial groove (Figure 1).
Note that the patient was circumcised. Dermoscopy found homogeneous Dotted vessels with some white scales on erythematous background (Figure 2).
What’s your diagnosis?
Exclusively Genital Psoriasis: Psoriasis is a chronic inflammatory skin disorder with a significant impact on social functioning . Genital psoriasis has semiotic and therapeutic features. It can be classified into 3 categories: exclusive genital location of psoriasis, genital psoriasis associated with inverted psoriasis, and genital location associated with non-inverted extra-genital psoriasis .
The exclusively genital form of psoriasis seems to be rare and is seen in only 2 to 5% of psoriatic patients . This is probably due to the modesty of patients about the discussion of the genital area, as well as the majority of patients do not know which doctor to consult, this ocalisation can affect the quality of life and be a source of marital problems .
Clinically, genital psoriasis is manifested by one or more small, welldefined erythematous plaques.
usually finely scaly in the circumcised subject and non-scaly in the uncircumcised, most often localized in the glans and the inner foreskin, but can reach the entire external genital tract  Sometimes the lesions may be accompanied by painful rhagades or fissures .
These lesions can be maintained by the Koebner effect given the location: urine, rubbing (tight clothing), sex, wearing a condom .
Dermosocpy shows red dots of homogeneous distribution and white scales on erythematous background.
The diagnosis of psoriasis is usually clinical and dermosocpy remains a non-invasive technique that facilitates it. However, unusual presentations do exist and may cause difficulties in differentiating from similar-looking inflammatory conditions. In such cases, histopathology plays a significant role in confirming the clinical diagnosis [8,9], objectifying at the level of the glans and of the inner face of the foreskin, where the epidermis and the dermis leave respectively place to the epithelium and the chorion, a constant parakeratosis, an exocytosis of neutrophils sometimes forming pustules, a psoriasiform acanthosis and a dermal lymphocytic infiltrate of variable intensity sometimes associated with plasma cells, in the rest of the external genital tract, the histology is similar to that of cutaneous psoriasis .
The treatment of genital psoriasis is generally based on topicals, as well as a good education to avoid the koebner effect. The recommended treatments for genital psoriasis are topical corticosteroids first-line, vitamin D preparations or tar based and immunomodulators should be considered after failure of topical corticosteroid. Phototherapy and laser therapy are not recommended in the genital area.