La Prensa Medica.ISSN: 0032-745X

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Research Article, Prensa Med Argent Vol: 101 Issue: 4

Therapeutic Options in Hypertrophic Cardiomyopathy

Abstract

 Therapeutic Options in Hypertrophic Cardiomyopathy

Hypertrophic cardiomyopathy (HCM) is one of the more common hereditary cardiac conditions. Several hundreds of mutations in genes coding for sarcomeric or energy metabolism proteins have been found to be associated with the phenotype. Myocardial disarray and fibrosis are the prominent histological findings of the disease. A more common (70%) obstructive (HOCM) has to be distinguished from the less common (30%) non-obstructive phenotype (HNCM). Symptoms include exercise limitation due to dyspnea or angina pectoris, palpitations, or dizziness.

Keywords: Hypertrophic obstructive cardiomyopathy; Percutaneous septal ablation, Myectomy, Risk stratification, Sudden cardiac death, ICD, HOCM, HCM, HNCM

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