International Publisher of Science, Technology and Medicine

 

Shivani Maffi

Shivani Maffi

Shivani Maffi, PhD
Department of Molecular Medicine
University of Texas Health Science Center, USA

 

Biography

 Shivani Maffi is currently working as researcher in Fetal Alcohol Spectrum Disorder, Addiction biology, Neuroscience, Mitochondrial trafficking, Confocal & Multiphoton Microscopy at University of Texas Health Science Center. Her specialties are Microscopy Consultancy.

Research Interest

Dr. Maffi's laboratory is interested in understanding mechanisms that control mitochondrial organization and trafficking in brain cells that are associated with several neurological disorders. Mitochondria control cell survival or cell death by performing multiple and sometimes dissimilar functions (energy metabolism, movement and programmed cell death) while responding to both endogenous as well as exogenous perturbations. This mitochondrial synergy and execution of their functions gains ultimate eminence in the long neuronal processes, where mitochondria are critically positioned. By using cellular, biochemical, state-of-the art microscopy and molecular biology techniques, Dr. Maffi studies how alcohol alters mitochondrial dynamics and induces oxidative stress. The present studies are not limited to alcohol but, simply used as a model system, given the clear link between alcohol and oxidative stress. The temporal movement and spatial distribution of mitochondria in cells has the potential to develop into a tool to differentiate between healthy and diseased cells.

Publications

Editors & Editorial Board Members
none:  Mol Med Ther 2012, 1:1
doi: #
#
Abstract  |   Full-text  |   PDF  |  
Editors & Editorial Board Members
none:  Mol Med Ther 2012, 1:2
doi:
Abstract  |   Full-text  |   PDF  |  
Human Fungal Infections: Need to Improve Diagnosis with New Biomarkers Developed by Translational Research
Editorial:  Mol Med Ther 2012, 1:1
doi: 10.4172/2324-8769.1000e101
Aamir Shahzad, Randall J Cohrs, Adong Shen and Cornelia Lass-Flörl
Abstract  |   Full-text  |   PDF  |  
Performance of Commercial Interferon-γ Release Assays for Screening Latent Tuberculosis Infection: A Meta-Analysis
Research Article:  Mol Med Ther 2012, 1:2
doi: 10.4172/2324-8769.1000103
Lin Sun, Qingqin Yin, Jianling Tian, Qing Miao, Fang Xu, Jing Xiao, Chen Shen, Weiwei Jiao, Cornelia Lass-Flörl, Aamir Shahzad and Adong Shen
Abstract  |   Full-text  |   PDF  |  
Parkinson’s Disease and Type-2 Diabetes: Methylglyoxal may be a Common Causal Agent; Carnosine could be Protective
Review Article:  Mol Med Ther 2012, 1:2
doi: 10.4172/2324-8769.1000104
Alan R. Hipkiss
Abstract  |   Full-text  |   PDF  |  
Prolyl Hydroxylases in fight or flight
Editorial:  Mol Med Ther 2012, 1:1
doi: 10.4172/2324-8769.1000e102
Anne-Theres Henze, Rodrigo Leite de Oliveira and Massimiliano Mazzone
Abstract  |   Full-text  |   PDF  |  
Genome-Scale Mapping of MicroRNA Signatures in Human Embryonic Stem Cell Neurogenesis
Research Article:  Mol Med Ther 2012, 1:2
doi: 10.4172/2324-8769.1000105
Xuejun H. Parsons, James F. Parsons and Dennis A. Moore
Abstract  |   Full-text  |   PDF  |  
Regulation of Coronary Vasomotor Function by Reactive Oxygen Species
Review Article:  Mol Med Ther 2012, 1:1
doi: 10.4172/2324-8769.1000101
Lih Kuo, Naris Thengchaisri and Travis W. Hein
Abstract  |   Full-text  |   PDF  |  
Novel Combinatorial Therapeutic Targeting of PAI-1(SERPINE1) Gene Expression in Alzheimer’s Disease
Short Communication:  Mol Med Ther 2012, 1:2
doi: 10.4172/2324-8769.1000106
Stacie M. Kutz, Craig E. Higgins and Paul J. Higgins
Abstract  |   Full-text  |   PDF  |  
Low Molecular Weight Antagonists of Plasminogen Activator Inhibitor-1: Therapeutic Potential in Cardiovascular Disease
Short Communication:  Mol Med Ther 2012, 1:1
doi: 10.4172/2324-8769.1000102
Tessa M. Simone and Paul J. Higgins
Abstract  |   Full-text  |   PDF  |  
 
izmit escort sex geschichten escort bayan porno sikis adult porno pornolar
test