Review Article, J Pharm Sci Emerg Drugs Vol: 5 Issue: 1
A Comprehensive Overview on Wound Healing and it’s Faster Curative Progression
*Corresponding Author : Harikesh Maurya
Department of Pharmacology, Siddhartha Institute of Pharmacy, Near I.T. Park, Sahastradhara Road, Dehradun, Uttarakhand, India
E-mail: [email protected]
Received: December 16, 2016 Accepted: January 20, 2017 Published: January 24, 2017
Citation: Maurya H, Goswami M, Gurung S, Harikumar SL, Yadav M (2017) A Comprehensive Overview on Wound Healing and it’s Faster Curative Progression. J Pharm Sci Emerg Drugs 5:1 doi: 10.4172/2380-9477.1000119
Wound is an injury concerning an external or internal breakdown of body tissues, mainly the outer membrane. Virtually every person will experience an unclosed wound at some point throughout their life. Mostly uncovered wounds are inconsequential and may be treated at home only. Wound healing requires a précised control for degradative and regenerative processes, which is involved in several types of cell and complex interactions between multiple biological processes in the living body. It is achieved throughout four precisely and synchronized programmed phases, i.e. homeostasis, inflammation, proliferation and remodelling. This composite process can be disrupted by local or systemic risk factors, resulting in delayed healing and progression to a chronic wound. Whereas, a complex chronic wound care may need a multi-disciplinary approach involving allied health members to provide additional nutritionary, nursing and psychosocial support. Basically it was observed that essential vitamins and minerals were required for wound repair which also involve in improving healing time for example; vitamin A is required for epithelialiazation, cellular differentiation, and immune function. Vitamin C is necessary for collagen formation, maintain proper immune function and act as an antioxidant potential. Vitamin E is the major sources of lipid-soluble antioxidant which required for skin protection. Bromelain and glucosamine reduces edema, bruising sensation, and intense pain, whereas it also recovers healing time during trauma and operative procedures. The herbal medicines Centella asiatica and Aloe vera have been used to enhance wound repair. To recover from wound healing within shortest time period with minimal pain, discomfort and scarring to the patient it is important to explore nutritional and herbal influences on wound outcome.