Yao-Shan Fan, MD, PhD, is a Professor of Pathology, Clinical Educator, and Director of Cytogenetics & Molecular Laboratory at University of Miami Miller School of Medicine. He graduated from Suzhou Medical College and received his PhD from Harbin Medical University. He completed 4 years of postdoctoral fellowship in Roswell Park Cancer Institute, New York, in the areas of cancer genetics and human molecular genetics, and then 2-year training in clinical cytogenetics at University of Alberta and one year additional training in clinical molecular genetics as McMaster University, Canada.
As a certified clinical cytogeneticist by Canadian College of Medical Geneticists (CCMG) and American Board of Medical Genetics (ABMG), he worked as a lab director, Assistant and Associate Professor at the University of Western Ontario, and the Chair of the Genetics Committee, Laboratory Proficiency Testing Program in Canada as well as a member of the CCMG Cytogenetics Committee. As one of the pioneers of FISH technology, he authored the book, “Molecular Cytogenetics: Protocols and Applications” and contributed to “Encyclopedia of Medical Genomics and Proteomics” as an Editorial Advisory. He was recognized by WHO’S WHO in 2003 for his exemplary achievement and awarded as one of The Best Doctors in America 2011-2012. His current research and services focuses on cytogenomic studies of developmental disorders and molecular diagnosis of human cancers.
Providing timely and accurate laboratory tests and precise interpretation of the results is my mandate. Current laboratory testing:
- Cytogenetic studies and fluorescence in situ hybridizaton (FISH) for daignosis and treatment of hematological malignancies.
- Molecular studies on biomarkers such as HER2, EGFR, KRAS and BRAF for targeted cancer therapies.
- Prenatal and postnatal diagnosis of developmental disorders including autism stectrum disorders caused by pathogenic genomic variations, using comparative genomic hybridization (CGH) and signal nucleotide polymorphim (SNP)arrays.
Human Fungal Infections: Need to Improve Diagnosis with New Biomarkers Developed by Translational ResearchEditorial: Mol Med Ther 2012, 1:1
Aamir Shahzad, Randall J Cohrs, Adong Shen and Cornelia Lass-Flörl
Performance of Commercial Interferon-γ Release Assays for Screening Latent Tuberculosis Infection: A Meta-AnalysisResearch Article: Mol Med Ther 2012, 1:2
Lin Sun, Qingqin Yin, Jianling Tian, Qing Miao, Fang Xu, Jing Xiao, Chen Shen, Weiwei Jiao, Cornelia Lass-Flörl, Aamir Shahzad and Adong Shen
Parkinsons Disease and Type-2 Diabetes: Methylglyoxal may be a Common Causal Agent; Carnosine could be ProtectiveReview Article: Mol Med Ther 2012, 1:2
Alan R. Hipkiss
- Editorial: Mol Med Ther 2012, 1:1
Anne-Theres Henze, Rodrigo Leite de Oliveira and Massimiliano Mazzone
- Research Article: Mol Med Ther 2012, 1:2
Xuejun H. Parsons, James F. Parsons and Dennis A. Moore
- Review Article: Mol Med Ther 2012, 1:1
Lih Kuo, Naris Thengchaisri and Travis W. Hein
- Short Communication: Mol Med Ther 2012, 1:2
Stacie M. Kutz, Craig E. Higgins and Paul J. Higgins
Low Molecular Weight Antagonists of Plasminogen Activator Inhibitor-1: Therapeutic Potential in Cardiovascular DiseaseShort Communication: Mol Med Ther 2012, 1:1
Tessa M. Simone and Paul J. Higgins