Biography
Dr. Liang Xu obtained his M.D. and Ph.D. in Gastroenterology at the Fourth Military Medical University of China in 1992 and did residency there. He did post-doc research on molecular biology at University of Louvain, Belgium, 1994, then at Stanford University, 1996. He moved to the Georgetown University and developed a novel non-viral tumor-targeted delivery system for cancer therapy, which is in Phase II clinical trials. In 2002, he joined the faculty at University of Michigan to discover the novel small molecule inhibitors of anti-apoptotic proteins. He is a co-inventor of the first Bcl-2 inhibitor that entered clinical trials. In 2010, he obtained a Rising Star Scholar Award and became an Associate Professor with Tenure at University of Kansas Cancer Center. He has >25 patents with four INDs in advanced clinical trials. He is now a Professor of Cancer Biology at University of Kansas and has been funded by NIH, DOD and Komen Foundation. He is now working on cancer drug discovery and immunotherapy targeting cancer stem cells.
Research Interest
Molecular therapy targeting cancer and cancer stem cells, via novel nanovectors and rational drug design.
Novel small-molecule cancer therapeutics - Drug discovery and molecular cancer therapy.
Novel nanovector delivery systems targeting cancer and cancer stem cells - Drug/gene delivery.
Related Publications
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The Study of Intestinal Permeability and its Relationship with Autism
Editorial: Res Rep Gastroenterol 2017, 1:1
DOI:
Menicagli R and Marotta O
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Gastric Schwannoma: A Rare Case with Preoperative Diagnosis by EUS-FNB
Clinical Image: Res Rep Gastroenterol 2018, 2:1
DOI:
Khamaysi I and Malkin L
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Inverted Meckels Diverticulum as the cause of Intussusception in Adults
Case Report: Res Rep Gastroenterol 2017, 1:1
DOI:
Shenouda M, Reid J, DeRogatis MJ, Gaspard S and Hinika G
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Primary Acquired Gastric Outlet Obstruction in Pediatrics (Jodhpur Disease) How to Manage? A Report of Two Cases
Case Report: Res Rep Gastroenterol 2018, 2:1
DOI:
Takrouney MH, Sabra TA, Ibrahim H and Ahmed MEL
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Successful Biliary Navigation Using Air in Malignant and Post-Surgical Hilar Strictures: A Prospective Controlled Trial
Research Article: Res Rep Gastroenterol 2018, 2:1
DOI:
Elshimi E, Attia AE, Eljaky A, Elshazly H and Allam M
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Hepatitis C Infection and Paroxysmal Nocturnal Hemoglobinuria with Complicated Course: Coincidental Association or True Link?
Case Report: Res Rep Gastroenterol 2017, 1:1
DOI:
Chakkor A, Arar A,Sanciu R,Legac E,Cacoub P and Ahmed SNS
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An Unusual Case of Dyspnoea in a Patient with Chronic Liver Disease
Case Report: Res Rep Gastroenterol 2018, 2:1
DOI:
Johnson A, Mitchell D, Batchelor S, Kaura S and Islam M
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Rectal Melanoma with Duodenal Metastasis: Very Unusual Endoscopic Findings
Case Report: Res Rep Gastroenterol 2017, 1:1
DOI:
Feldman D, Mari A, Abu-Backer F and Kopelman Y
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Crohns Colitis with Marked Peripheral Eosinophilia
Case Report: Res Rep Gastroenterol 2017, 1:1
DOI:
Matar K, Helal A, Yaacoub A and Mari A
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Perforated Sigmoid Volvulus in an Elderly Male with Expressive Aphasia
Case Report: Res Rep Gastroenterol 2018, 2:1
DOI:
Steven KM Vuu, Tania Zavalza Jimenez, Carlos E Ramirez, Michael J DeRogatis* and Gudata Hinika
