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John C. Weber

John C. Weber

John C. Weber, PhD
Faculty of Medicine
Memorial University of Newfoundland, Canada

 

Biography

Dr. John Weber is an Associate Professor, Cross Appointment to Faculty of Medicine at Memorial University of Newfoundland, Canada. He earned his PhD in Pharmacology and Toxicology from the Medical College of Virginia.

Research Interest

His current research program has two major areas of focus. The first area is studying the mechanisms that contribute to altered physiology and pathology associated with the cerebellum, an area of the brain associated with fine motor coordination and motor learning. This line of studies includes behavioral analysis of ataxic mutant mouse models, and the effects of adolescent alcohol exposure on long-term motor function and cell physiology. In addition to behavioral analyses, we measure alterations in calcium signaling in various cells of the cerebellum using fluorescent imaging techniques in cerebellar slices derived from rats or mice. We also plan to conduct electrophysiology measurements in cerebellar cells primarily using the whole-cell patch-clamp technique.

His second major area of research involves the study of agents that can protect the brain from traumatic insults and the aging process, particularly substances derived from natural products (e.g. species of berries native to Newfoundland and Labrador; oxyresveratrol). In this line of research I primarily utilize cell cultures from various brain regions and analyze biomarkers associated with neurodegenerative diseases as cells age, or after they are injured with in vitro models that produce mechanical strain, meant to mimic traumatic brain injury.

Publications

Anticancer Potential of Plants and Natural Products: A Review
Review Article:  J Pharmacol Biomed Anal 2013, 1:2
doi: 10.4172/2327-4638.1000103
Rahul Dev Lawania and Anurag Mishra
Abstract  |   Full-text  |   PDF  |  
Effects of Aqueous Extract of Phyllanthus muellerianus Leaves on Castor Oil-induced Diarrhoeal Rats
Research Article:  J Pharmacol Biomed Anal 2013, 1:2
doi: 10.4172/2327-4638.1000104
Bamisaye FA, Oloyede OB and Yakubu MT
Abstract  |   Full-text  |   PDF  |  
Endoplasmic Reticulum Stress and Related Pathological Processes
Review Article:  J Pharmacol Biomed Anal 2013, 1:2
doi: 10.4172/2327-4638.1000105
Yu Mei, Melissa D Thompson, Richard A Cohen and XiaoYong Tong
Abstract  |   Full-text  |   PDF  |  
Sample Collection Procedures and Impact on QuantiFERON®-Gold in Tube Results
Short Article:  J Diagn Tech Biomed Anal 2016, 5:1
doi: 10.4172/2469-5653.1000112
Pascal Bittel
Abstract  |   Full-text  |   PDF  |  
Hyperglycemia and Tumor Energy Metabolism
Editorial:  J Pharmacol Biomed Anal 2013, 1:1
doi: 10.4172/2327-4638.1000e101
J?zef Oleksyszyn
Abstract  |   Full-text  |   PDF  |  
The Sterol Regulatory Element Binding Transcription Factor 1 (SREBP1): An Attractive Therapeutic Target in CNS Drug Discoveries
Editorial:  J Pharmacol Biomed Anal 2013, 1:1
doi: 10.4172/2327-4638.1000e102
Changiz Taghibiglou
Abstract  |   Full-text  |   PDF  |  
Incidence of Infectious Mononucleosis in Universities and U.S. Military Settings
Short Communication:  J Diagn Tech Biomed Anal 2016, 5:1
doi: 10.4172/2469-5653.1000113

Yolonda J Williams-Harmon, Leonard A Jason, and Ben Z. Katz

Abstract  |   Full-text  |   PDF  |  
Cost-Effectiveness Analysis of Diagnostics Tests of Respiratory Tract Infection in Cancer Patients
Research Article:  J Diagn Tech Biomed Anal 2016, 5:1
doi: 10.4172/2469-5653.1000114
Teresa Maria Furlan, Eduardo Massad  and Saulo Duarte Passos
Abstract  |   Full-text  |   PDF  |  
The Effects of 1-Aminobenzotriazole Inhibition on the Formation of Acyl-Glucuronide and Acyl-Glutathione Metabolites in Rat Hepatocytes
Research Article:  J Diagnos Tech Biomed Anal 2014, 2:1
doi: 10.4172/2469-5653.1000106
Howard Horng and Leslie Z. Benet
Abstract  |   Full-text  |   PDF  |  
Availability of Different Strengths of Anti Malarial Preparations in Pakistan: Implication for Patient Safety
Letter to Editor:  J Pharmacol Biomed Anal 2013, 1:1
doi: 10.4172/2327-4638.1000101
Malik M, Hassali MA, Shafie AA, Hussain A and Aljadhey H
Abstract  |   Full-text  |   PDF  |  
Novel Evaluation of Intravoxel Incoherent Motion Using Fourier Analysis for Prostate Cancer Detection
Research Article:  J Diagn Tech Biomed Anal 2016, 5:1
doi: 10.4172/2469-5653.1000115
Akio Ogura, Fumie Maeda and Katsumi Hayakawa
Abstract  |   Full-text  |   PDF  |  
Are Both Antidepressant Drug Effects and Test Scores Unspecific?
Research Article:  J Pharmacol Biomed Anal 2013, 1:1
doi: 10.4172/2327-4638.1000102
Ivar Aursnes, Ingunn F Tvete, Jorund Gaasemyr, Bent Natvig and Marianne Klemp
Abstract  |   Full-text  |   PDF  |  
Role of Oxidative Stress in Male Fertility and Idiopathic Infertility: Causes and Treatment
Review Article:  J Diagnos Tech Biomed Anal 2014, 2:1
doi: 10.4172/2469-5653.1000107
Doaa A. Ghareeb, Eman M.E. Sarhan
Abstract  |   Full-text  |   PDF  |  
Bacillus Calmette-Gu�rin (BCG) Vaccine-Induced Disease in Healthy Infants: Identification of BCG Gene from Formalin-Fixed Paraffin-Embedded Tissue
Research Article:  J Diagnos Tech Biomed Anal 2014, 2:1
doi: 10.4172/2469-5653.1000108
Takako Yoshioka, Junichiro Nishi, Kiyofumi Ohkusu, Kazuhito Hatanaka, Sohsuke Yamada, Kazuhiko Nakame, Yoshifumi, Kawano, Tatsuru Kaji, Akihide Tanimoto
Abstract  |   Full-text  |   PDF  |  
Local Tissue Damage as a Possible Trigger to Giant Cell’s Inflammatory Response and Failure Following Trapezectomy and Interposition of Polylactic Acid Arex Trapezium Implant: A Case Report.
Case Report:  J Diagnos Tech Biomed Anal 2014, 2:1
doi: 10.4172/2469-5653.1000109
Lauren Gorelick, Ayala Rozano-Gorelick, Anwar Saab, Edward Ram
Abstract  |   Full-text  |   PDF  |  
Comparing HPLC Stationary Phases for The Separation of Six Compounds Used in Pain Management: Is There a Viable Alternative to C18?
Research Article:  J Diagnos Tech Biomed Anal 2014, 2:2
doi: 10.4172/2469-5653.1000110
Derek Stallard, Stacy Brown
Abstract  |   Full-text  |   PDF  |  
Application Of Color Changes Of Anthocyanins In Red Wine And Red Currant Extract As A Clinical PH Indicator
Research Article:  J Diagn Tech Biomed Anal
doi: 10.4172/2469-5653.1000111
Wataru Sakamoto, Takashi Kanehira, Hirohisa Hongou, Akemi Matsuda, Masanori Mune and Kozo Asano
Abstract  |   Full-text  |   PDF  |  
 
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