International Publisher of Science, Technology and Medicine


Sara E. Rosenbaum

Sara E. Rosenbaum

Sara E. Rosenbaum, PhD
College of Pharmacy
University of Rhode Island, USA



Dr. Sara Rosenbaum is Professor of Pharmacokinetics at the University of Rhode Island and is involved in teaching and research in the broad area of clinical pharmacokinetics and pharmacodynamics. She is interested in applying modeling and simulation of drug response data as tools to more fully understand the time course and intensity of drug effects in man. She is interested in applying these methods in research to obtain a greater understanding of a drug’s properties in different populations. She also develops interactive pharmacokinetic and pharmacodynamic models to demonstrate fundamental drug properties. Sara Rosenbaum has recently published a book, Basic Pharmacokinetics and Pharmacodynamics: An Integrated Textbook with Computer Simulations, which provides a comprehensive account of essential pharmacokinetic and pharmacodynamic concepts. The textbook also incorporates interactive pharmacokinetic and pharmacodynamic simulation models to allow students to visualize important principles and experiment with the design of drug dosing regimens.

Research Interest

The population approach to modeling and NONMEM are used to develop structural and statistical pharmacokinetic and pharmacodynamic models. Patient demographics are probed as potential covariates for pharmacokinetic and/or pharmacodynamic parameters. The objective of the research is to identify patient characteristics that result in altered pharmacokinetic or pharmacodynamic parameters and to allow optimum drug doses to be identified in diverse patient groups. The research has involved drugs from many different therapeutic areas.


Anticancer Potential of Plants and Natural Products: A Review
Review Article:  J Pharmacol Biomed Anal 2013, 1:2
doi: 10.4172/2327-4638.1000103
Rahul Dev Lawania and Anurag Mishra
Abstract  |   Full-text  |   PDF  |  
Effects of Aqueous Extract of Phyllanthus muellerianus Leaves on Castor Oil-induced Diarrhoeal Rats
Research Article:  J Pharmacol Biomed Anal 2013, 1:2
doi: 10.4172/2327-4638.1000104
Bamisaye FA, Oloyede OB and Yakubu MT
Abstract  |   Full-text  |   PDF  |  
Endoplasmic Reticulum Stress and Related Pathological Processes
Review Article:  J Pharmacol Biomed Anal 2013, 1:2
doi: 10.4172/2327-4638.1000105
Yu Mei, Melissa D Thompson, Richard A Cohen and XiaoYong Tong
Abstract  |   Full-text  |   PDF  |  
Sample Collection Procedures and Impact on QuantiFERON®-Gold in Tube Results
Short Article:  J Diagn Tech Biomed Anal 2016, 5:1
doi: 10.4172/2469-5653.1000112
Pascal Bittel
Abstract  |   Full-text  |   PDF  |  
Hyperglycemia and Tumor Energy Metabolism
Editorial:  J Pharmacol Biomed Anal 2013, 1:1
doi: 10.4172/2327-4638.1000e101
J?zef Oleksyszyn
Abstract  |   Full-text  |   PDF  |  
The Sterol Regulatory Element Binding Transcription Factor 1 (SREBP1): An Attractive Therapeutic Target in CNS Drug Discoveries
Editorial:  J Pharmacol Biomed Anal 2013, 1:1
doi: 10.4172/2327-4638.1000e102
Changiz Taghibiglou
Abstract  |   Full-text  |   PDF  |  
Incidence of Infectious Mononucleosis in Universities and U.S. Military Settings
Short Communication:  J Diagn Tech Biomed Anal 2016, 5:1
doi: 10.4172/2469-5653.1000113

Yolonda J Williams-Harmon, Leonard A Jason, and Ben Z. Katz

Abstract  |   Full-text  |   PDF  |  
Cost-Effectiveness Analysis of Diagnostics Tests of Respiratory Tract Infection in Cancer Patients
Research Article:  J Diagn Tech Biomed Anal 2016, 5:1
doi: 10.4172/2469-5653.1000114
Teresa Maria Furlan, Eduardo Massad  and Saulo Duarte Passos
Abstract  |   Full-text  |   PDF  |  
The Effects of 1-Aminobenzotriazole Inhibition on the Formation of Acyl-Glucuronide and Acyl-Glutathione Metabolites in Rat Hepatocytes
Research Article:  J Diagnos Tech Biomed Anal 2014, 2:1
doi: 10.4172/2469-5653.1000106
Howard Horng and Leslie Z. Benet
Abstract  |   Full-text  |   PDF  |  
Availability of Different Strengths of Anti Malarial Preparations in Pakistan: Implication for Patient Safety
Letter to Editor:  J Pharmacol Biomed Anal 2013, 1:1
doi: 10.4172/2327-4638.1000101
Malik M, Hassali MA, Shafie AA, Hussain A and Aljadhey H
Abstract  |   Full-text  |   PDF  |  
Novel Evaluation of Intravoxel Incoherent Motion Using Fourier Analysis for Prostate Cancer Detection
Research Article:  J Diagn Tech Biomed Anal 2016, 5:1
doi: 10.4172/2469-5653.1000115
Akio Ogura, Fumie Maeda and Katsumi Hayakawa
Abstract  |   Full-text  |   PDF  |  
Are Both Antidepressant Drug Effects and Test Scores Unspecific?
Research Article:  J Pharmacol Biomed Anal 2013, 1:1
doi: 10.4172/2327-4638.1000102
Ivar Aursnes, Ingunn F Tvete, Jorund Gaasemyr, Bent Natvig and Marianne Klemp
Abstract  |   Full-text  |   PDF  |  
Role of Oxidative Stress in Male Fertility and Idiopathic Infertility: Causes and Treatment
Review Article:  J Diagnos Tech Biomed Anal 2014, 2:1
doi: 10.4172/2469-5653.1000107
Doaa A. Ghareeb, Eman M.E. Sarhan
Abstract  |   Full-text  |   PDF  |  
Bacillus Calmette-Gu�rin (BCG) Vaccine-Induced Disease in Healthy Infants: Identification of BCG Gene from Formalin-Fixed Paraffin-Embedded Tissue
Research Article:  J Diagnos Tech Biomed Anal 2014, 2:1
doi: 10.4172/2469-5653.1000108
Takako Yoshioka, Junichiro Nishi, Kiyofumi Ohkusu, Kazuhito Hatanaka, Sohsuke Yamada, Kazuhiko Nakame, Yoshifumi, Kawano, Tatsuru Kaji, Akihide Tanimoto
Abstract  |   Full-text  |   PDF  |  
Local Tissue Damage as a Possible Trigger to Giant Cell’s Inflammatory Response and Failure Following Trapezectomy and Interposition of Polylactic Acid Arex Trapezium Implant: A Case Report.
Case Report:  J Diagnos Tech Biomed Anal 2014, 2:1
doi: 10.4172/2469-5653.1000109
Lauren Gorelick, Ayala Rozano-Gorelick, Anwar Saab, Edward Ram
Abstract  |   Full-text  |   PDF  |  
Comparing HPLC Stationary Phases for The Separation of Six Compounds Used in Pain Management: Is There a Viable Alternative to C18?
Research Article:  J Diagnos Tech Biomed Anal 2014, 2:2
doi: 10.4172/2469-5653.1000110
Derek Stallard, Stacy Brown
Abstract  |   Full-text  |   PDF  |  
Application Of Color Changes Of Anthocyanins In Red Wine And Red Currant Extract As A Clinical PH Indicator
Research Article:  J Diagn Tech Biomed Anal
doi: 10.4172/2469-5653.1000111
Wataru Sakamoto, Takashi Kanehira, Hirohisa Hongou, Akemi Matsuda, Masanori Mune and Kozo Asano
Abstract  |   Full-text  |   PDF  |  
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