Dr. Rui-An Wang received his M.D degree from Nanfang Medical University, and his Ph.D degree from the 3rd Military Medical University of China. He had been a lecturer of histology for years and then did his postdoctoral training in USA, at M.D.Anderson Cancer Center and worked as a faculty there for eight years. His scientific research experience has been very extensive, as in the field of endocrinology, male reproductive biology, developmental biology and cancer biology. His publications include those high rank journals as Nature, Nature Cell Biology, EMBO J, JCB, PNAS, Oncogene, etc. He is now a professor of pathology of the Fourth Military Medical University of China. What is special of him is that he proposed a new cancer theory, the stem cell misplacement theory, which posits that in situ carcinoma is not cancer, nor the origin of invasive cancer. The invasive cancer grows out de novo in the stroma fromdislodged epithelial stem cells. Apoptosis, instead of being a barrier of carcinogenesis as generally believed, stimulates carcinogenesis, cancer growth and metastasis.
Theory and mechanisms of carcinogenesis and metastasis; breast cancer; endocrinology